That's the conclusion of a
Mayo Clinic study in the June
1 issue of Circulation.
The
human body maintains a balance of blood pressure
and blood flow by expanding
or contracting blood vessels," study
leader and cardiologist Dr.
Virend Somers said in a prepared
statement. "Much of this expansion
is directed by a layer of cells
called the endothelium, which
lines the blood vessels. Risks
of sudden death, heart attack
and stroke are 30 to 50 percent
higher in the early morning
hours, so we wanted to determine
whether the endothelium's effects
are diminished in the morning," Somers
said.
The
study included 30 healthy nonsmokers.
Their endothelial function was
measured at bedtime, 6 a.m. and
11 a.m. The results showed their
endothelial function was reduced
by more than 40 percent in the
early morning but was normal again
by later morning.
Early
morning endothelial function in these healthy
subjects was similar to that seen in smokers
and people with diabetes |